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Furthermore, combining TMB with HRD scoring can provide clinicians with more comprehensive patient information, thereby optimizing treatment plans and improving patient survival rates and quality of life (97)

Oh et al., 2024

Similar to photoreceptors, the post-mitotic nature of RPE cells preclude the rapid clearance of damaged mitochondria through cell division (Plafker et al., 2012)

Taken together, these findings suggest a complex relationship among normal ROS flux, heightened ROS generation, and (patho)biological processes that can be regulated, in part, by GPx-1