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To further enhance the clinical utility of serum GR, future studies should include a broader range of populations, such as children, adolescents, and pregnant women, as well as participants from diverse geographic regions

doi: 10.1186/1471-2164-15-1122 198 RoosendaalJ.WestawayE

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Wilson's disease The protein, ATP7B, is responsible for the excretion of hepatic copper into the biliary tract, and its impairment in Wilson's disease results in an increased concentration of 'free' copper (i.e., not bound to the copper-carrying protein, ceruloplasmin) in blood, an increased excretion of copper in the urine (hypercupriuria), the deposition of copper in part of the cornea (forming Kayser-Fleischer rings), and the accumulation of copper in the liver and brain (106)

Serotonergic gene-to-gene interaction is associated with mood and GABA concentrations but not with pain-related cerebral processing in fibromyalgia subjects and healthy controls