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While the exact mechanism associated with this oxygen sensitivity is unclear, we propose that the enhanced oxygen sensitivity may be tied to a more open active site cleft in T-Mac (Appendix Fig

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Initial intensive therapy (daily-weekly injections) typically lasts 1-2 months, followed by lifelong monthly maintenance for chronic conditions

Fenretinide (4-HPR) targets caspase-9, ERK 1/2 and the wnt3a/-catenin pathway in medulloblastoma cells and medulloblastoma cell spheroids

Models induced by scopolamine combined with therapeutic agents such as curcumin [9] provide an opportunity to study the effects of the memory impairment over the course of time and to understand neurobiological processes