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Bioengineered MSC-Exos can encapsulate targeted therapeutic agents, including miRNAs, proteins, and drugs

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Current knowledge only partially explains how distinct TAM subsets, such as inflammatory M1-like macrophages, immunosuppressive M2-like macrophages, lipid-associated TAMs, and embryonically derived tissue-resident macrophages, differ in their ability to induce or restrain ferroptosis within tumors