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Neurological damage: Promote neuroprotection and helps in recovery from neurological impairments

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A pooled analysis of four major clinical trials ( N = 2551) found that higher baseline CRP levels predicted smaller reductions in depressive symptoms after treatment with standard antidepressants, particularly SSRIs [16 ], replicating earlier findings of reduced responsiveness to serotonergic and noradrenergic agents in the presence of inflammation [49,56]

A 2025 review by Jozwiak and colleagues surveys the peptides multifunctionality and possible medical applications (PMC11859134), and is a useful map of what has and has not been established

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