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The discrepancies in the biotoxicity of ferroptosis-inducers in animal models and humans contribute to erroneous assessments of the safety and efficacy of therapies

Li Y, He X, Sun B, Hu N, Li J, You R et al (2024) Combined exposure of beta-cypermethrin and emamectin benzoate interferes with the HPO axis through oxidative stress, causing an imbalance of hormone homeostasis in female rats

Vascular superoxide is primarily derived from nicotinamide adenine dineucleotide phosphate (NADPH) oxidase when stimulated by hormones, such as angiotensin II (AT-II), endothelin-1 (ET-1) and urotensin II

Crucially, these measures would help reduce flood risk further downstream, protecting the citys historic centre in sharp contrast to current UK policy, which too often sees agricultural land protected with flood defences at the expense of towns downstream