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The 1-year mortality rate among cirrhosis patients with ascites reaches 15%, while the 5-year mortality rate can soar as high as 44% ( Liver cirrhosis and upper gastrointestinal bleeding Liver cirrhosis is often accompanied by multiple system involvement, and complications such as upper gastrointestinal bleeding and secondary infection often occur in the late stage

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This finding proved the viability of the AMA pathway for converting lysine into glutarate