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Clinical spectrum of immunodeficiency, centromeric instability and facial dysmorphism (ICF syndrome)

In Vitro 3-hydroxy-acetaminophen scavenges free radicals through the electron donation ability of the phenolic hydroxyl group, showing antioxidant activity and can reduce cellular oxidative damage [2]

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Furthermore, in vitro experiments have suggested that increased depletion of GSH results in selective impairment of mitochondrial complex I activity (23)

Schultz MB, Sinclair DA