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A aggregation and tau hyperphosphorylation can disrupt the calcium balance in neurons, leading to mitochondrial calcium overload, increased reactive oxygen species production, reduced ATP generation, and ultimately, neuronal apoptosis or necrosis [76, 77]

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Once reconstituted, use the solution within a timeframe consistent with your labs standard operating procedures for peptide solutions, and avoid repeated freeze-thaw cycles, which can compromise peptide integrity

doi: 10.1006/bbrc.1998.9729 23 ZavadskisSWeidingerAHanetsederDBanerjeeASchneiderCWolbankSet al

Keep this in mind when you are getting your supplies together and arranging someone to help you