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These heart rate and blood pressure shifts, while usually modest, may require dose adjustments or additional cardiac monitoring if you have a pacemaker

Valenti D, de Bari L, de Filippis B, Henrion-Caude A, Vacca RA

Inulin-type fructan intervention restricts the increase in gut microbiome-generated indole in patients with peritoneal dialysis: a randomized crossover study