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Methylmercury can act as a neurotoxin and bioaccumulates in the tissues of aquatic plants and animals and can affect the health of individuals who eat these animals and fishes

doi: 10.1016/j.biocel.2010.06.001 38

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Sensitivities and pharmacokinetics of melatonin vary between individuals, and a lower dose of 0.3-0.5 mg might be more effective than higher doses in many subjects