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Pb significantly reduced the activities of all studied enzymes except CAT and DHAR in both leaves and roots

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For most peptides, the PK and PD timescales are tightly linked: when serum concentration falls, effect diminishes

FIGURE 6 3.4 Proteostasis and autophagy Polyphenols, a heterogeneous collection of naturally occurring chemicals present in plants, have a substantial impact on regulating proteostasis and autophagy, which are essential mechanisms in neuroinflammation and neurodegenerative disorders (Rahman et al., 2023)