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Additionally, many studies have been conducted outside the UK, and results may not directly translate to NHS patient populations

Jiang Y, Wang X, Hu D

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Scope Adults presenting to the ED with migraine (any ICHD version) Parenteral therapies only (injectable medications and nerve blocks) Randomized controlled trials reporting outcomes within 6 hours Comparators: placebo, sham, or another parenteral therapy Studies included in the 2016 AHS guideline were excluded Evidence Review A systematic review was registered with PROSPERO, approved by the AHS Guideline Committee, and PRISMA guidelines were followed