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those who may experience more anxiety and irritability) may benefit from a dosage reduction, in the case that their pathways are moving too quickly

This medication is susceptible to misuse and addiction, contributing to the opioid crisis

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For acute studies specifically, lower lactate levels (21, 29), increased power output (29), increased VO 2peak (29), and increased time to exhaustion (8) have been reported, while other groups displayed no changes in physiological or performance variables (2, 4, 9, 17)