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Description

Frystyk J

2 AdairJ

M2 macrophage polarization

The xenobiotic adaptation in arthropods evolves through multiple mechanisms (Figure 1) [13, 14], including reduced penetration through the cuticle, behavioral avoidance [15, 16], microbiome-mediated detoxification [17-20], enhanced metabolic detoxification [21-25], enhanced sequestration or excretion [13, 19, 26, 27], and target site insensitivity [28-32]

Metabolic studies Metabolic assessments were conducted using a Phenomaster (TSE systems) at Soonchunhyang Biomedical Research Core-facility of Korea Basic Science Institute (KBSI)