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When sufficient oxygen cannot be utilized, i.e., hypoxia, the citric acid cycle stops metabolizing pyruvate to obtain ATP, instead progressively generating lactate

In practical terms, the research-backed portion of the formula is the 300mg standardized extract, while the added root powder is better viewed as a supporting inclusion

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Ovarian cancer incidence and death in average-risk women undergoing bilateral salpingo-oophorectomy at benign hysterectomy

Ye BJ, Kim BG, Jeon MJ, Kim SY, Kim HC, Jang TW, Chae HJ, Choi WJ, Ha MN, Hong YS