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Agents 56:106054

These include NLRP3 itself, NLRP3-dependent caspase-1 activation, and IL-1 maturation [15]

Using random forest regression as the predictive model, we identified pathways commonly associated with NRF2, such as reactive oxygen species (ROS) and xenobiotic metabolism, in addition to reduced glutathione and NADP levels, as top features associated with NRF2 dependency (Fig