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LVO patients directly attended at an MT-C were more frequently treated with MT when M-DIRECT positive (77% vs 41%) despite similar NIHSS [median (IQR) 17 (11-22) vs 17 (7-21)] and consistently across every arterial segment (ICA, M1, M2, ACA, PCA, other)

The appearance of a pronucleus was used as the indicator of successful activation, suggesting that the oocyte had completed meiotic maturation and was capable of initiating embryonic development independently of fertilization

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Inner Mong J Tradit Chin Med 2010;29:24