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Nat Rev Micro/Nature Publishing Group, a division of Macmillan Publishers Limited

antioxidants may also produce free radicals (Weir et al., 1996)

The upregulation of miR-503-5p mediated the inhibitory effect of MM on HUVEC viability, as well as its promotive effect on oxidative stress and proinflammatory cytokine (IL-6 and TNF-) expression, which demonstrated that miR-503-5p is a mediator of MM-induced HUVEC injury