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As defined by Arthur Riggs and colleagues, it is "the study of mitotically and/or meiotically heritable changes in gene function that cannot be explained by changes in DNA sequence." [21] The term has also been used, however, to describe processes which have not been demonstrated to be heritable, such as some forms of histone modification

Leamy, A

Micro Pathog

Science 217 : 12631265 Town M, Jean G, Cherqui S, Attard M, Forestier L, Whitmore SA, Callen DF, Gribouval O, Broyer M, Bates GP, van't Hoff W, Antignac C 1998 A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis

Numerous studies have demonstrated the involvement of the NF-B pathway in the development of IBD