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In osteoblasts lacking classical ER and ER, the expression and activation of GPER can mediate the biological effects of estrogen, demonstrating its key role in bone metabolism [143, 147]

In the final tree, only one branch had a clade credibility value less than 100 (i.e., a branch that placed C

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Statins lower triglyceride levels by reducing the production of VLDL in the liver, which is a major carrier of triglycerides in the blood as discussed previously

Other modified proteins were extracellular matrix proteins and proteins involved in the degradation thereof (such as Col6a1 , Ctsb , Ctsd , Hspg2 , Plg , and Vtn ) and cytoskeletal proteins (such as Flna, Syne2 , Tbcc , and Lpp )