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The NRF-2 pathway aids the antioxidant mechanism with necessary compounds to protect against the OS, which will not be found in excessive situations and which can be maintained under control [8,9]

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nevertheless, supplementation of NSO and NSS mitigated this adverse effect to varying degrees through their antioxidant, anti-inflammatory, and anti-apoptotic properties, which underlie their protective performance against hepatorenal damage in response to AZA administration

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