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This heptapeptide, derived from the naturally occurring human tetrapeptide Tuftsin, has been shown to possess a wide range of biological activities, including enhancing memory, reducing anxiety, and potentially mitigating the effects of neurodegenerative diseases

The relative arrangement between these side chains and the catalytic Ser657 limits the active site and leaves room for only two amino acids before the scissile bond reaches the catalytic Ser657, making DAP BII a dipeptidyl peptidase

Animal studies show substantial evidence across stroke models (full functional recovery in spatial memory, motor coordination, balance), Parkinsons models (protection of dopaminergic neurons, near-complete prevention of mortality), multiple sclerosis models (significantly less brain damage), and traumatic brain injury (reduced hemorrhage and edema)

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