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References: [1] S

Trajectories of brain development: point of vulnerability or window of opportunity

Detoxification Glutathione-S-transferase () 2

In addition, OP toxicity in humans has been linked to mitochondrial dynamics and neurotrophins

The complete removal of intronic regions flanking the GAA repeats showed the most significant restoration of FXN expression, compared to elimination of only the GAA tract, offering a potential therapeutic strategy for FRDA