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2) Nitric oxide (NO) generated by nitric oxide synthase (NOS) disrupts IL-2 signaling via inhibition of JAK-STAT, ERK, and AKT phosphorylation, destabilizing IL-2 and inducing T-cell apoptosis (188191)

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The phenol OH hydrogen is not located in the crystal structure determination but is assumed to be present

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One is that, I mean, traumatic brain injury, it's terrible, but it's so interesting because it's also literal real-time brain aging