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Dehalogenase Mechanisms Rather than through reductive dechlorination, anaerobic degradation of chloromethane occurs via a corrinoid-dependent methyl transfer system (Traunecker et al., 1991), and hence is similar to the mechanism employed by aerobic methylotrophic bacteria capable of assimilating chloromethane (Figure 4F)

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Topical vitamin A, like retinoic acid (also known as tretinoin or retinoids), may be the right option for you