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In the non-enzymatic pathway, the excessive Fe 2+ firstly reacts with ROS to generate OH via the Fenton reaction (75), which then leads to the abstraction of hydrogen from PUFA-PL and the production of PUFA-PL (70)

Among the hematological factors, the leukocyte count demonstrated the highest correlation with oxidative stress factors, followed by the total band cell count and neutrophil count

Interestingly, these iNSCs have demonstrated all the characteristics of normal NSCs, boasting the ability to differentiate into astrocytes, neurons, and oligodendrocytes

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Astaxanthin promotes Nrf2/ARE signaling to inhibit HG-induced renal fibrosis in GMCs