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Studies have shown that glabridin can inhibit the development of inflammation, reduce collagen production, and alleviate scar hyperplasia in rabbit ears by regulating the PI3K/Akt and TGF-1/Smad pathways ( Oxidative stress refers to a pathological state in which excessive reactive oxygen species (ROS) are produced in the body or cells, or the function of the antioxidant system is impaired, leading to ROS accumulation and oxidative damage

The other pathway involves the activation of SOAT1 (sterol O-acyltransferase 1) in pancreatic cancer and leukemia cells, leading to the production of PUFA-cholesteryl esters instead of PUFA-phosphatidylethanolamines [91]

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AY is Editor of Journal of Psychopharmacology and Deputy Editor, BJPsych Open, Executive Officer of the International Society for Affective Disorders, a Committee Member of the British Association of Psychopharmacology, and Chair, Academic Faculty, Royal College of Psychiatrists

For instance, Che et al