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Infusion of Ang IV directly in renal arteries was reported to increase renal CBF in anesthetized rats as measured by laser Doppler flowmetry, 60, 126 an effect blocked by the specific AT 4 receptor antagonist, Divalinal-Ang IV, but not by selective AT 1 and AT 2 receptor antagonists

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Types of dementia that may be treated as described herein include but are not limited to Alzheimer's Disease (AD), vascular dementia, dementia with Lewy bodies, mixed dementia, etc