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Moreover, the SYNERGY-NASH trial showed that tirzepatide was associated with a dose-dependent greater likelihood of biopsy-proven MASH resolution vs

Patskovsky YV, Patskovska LN, Listowsky I

doi: 10.1038/s41556-018-0124-1 58 OliveiraGLCoelhoARMarquesROliveiraPJ

While the ultimate goal of the geroscience approach is to extend healthy lifespan by delaying or preventing disease, the lack of specific biomarkers for senescent cells (fluid, imaging, etc.) represents a major hurdle for identifying participants that may most benefit from senolytics