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The NMN dose in this study was fixed after considering the dose in previously reported NR trials (1002000 mg/day) and ongoing NMN clinical trials (100, 200, and 250 mg/day)

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People may need B12 injections if they: Have a vitamin B12 deficiency (due to poor absorption, medical conditions, or dietary choices) Are vegetarians or vegans (B12 is mostly found in animal-based foods) Have digestive disorders like Crohns disease, celiac disease, or low stomach acid Are older adults (since absorption decreases with age) Take medications like metformin or proton pump inhibitors that interfere with B12 absorption Have undergone weight-loss surgery, which can affect absorption What are the Benefits of B12 Shots