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Sedelnikova OA, Redon CE, Dickey JS, Nakamura AJ, Georgakilas AG, Bonner WM

Similar effects were observed in the brain of mice exposed to aspartame at doses up to 45 mg/kg bw or 5.625 mg/kg bw per day by single or multiple (for 2 weeks) subcutaneous injections, respectively

Excess copper enters via CTR1, and excess ROS reduces GSH and drives OX-LDL production, contributing to atherosclerosis, Drp1-mediated fission, mPTP opening, and ultimately cuproptosis

Furthermore, efficient monitoring of biological rhythms requires the implementation of continuous and noninvasive methods

TXNIP is an endogenous thioredoxin inhibitor that was later found to be elevated in rodent models of diabetes and has therefore been associated with the -cell response to stress (59)