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This implies both physical and mental stress

Thiamine overdose doesn't cause toxicity

Yes, many report healing from years-old damage How fast does it work

In most of the reported cases, these events followed tonsillectomy and/or adenoidectomy, and many of the children had evidence of being ultra-rapid metabolizers of codeine (i.e., multiple copies of the gene for cytochrome P450 isoenzyme 2D6 or high morphine concentrations)