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DeepContrast visualizes functional lesions in aging and Alzheimer's disease brains We generated GBCA-predicted maps from non-contrast T1-weighted MRI scans with DeepContrast, and subsequently quantified synthesized CBV maps with a sub-millimeter in-plane resolution of 0.680.68 mm in the coronal planes and slice thickness of 3 mm (refer to Methods)

J.MendozaK.KakadiarisE.RoyT.et al (2019)

Nimmo MA, Leggate M, Viana JL, King JA

Results APR-246 induces ferroptosis in acute myeloid leukemia cells In order to determine the activity of APR-246 in AML, we assayed a set of 12 AML cell lines carrying diverse and representative molecular abnormalities, and five primary AML samples ( Online Supplementary Table S1 )

Classic hyperglycemic symptoms: Polydipsia (excessive thirst) Polyuria (frequent urination) and nocturia Polyphagia (excessive hunger) with unexplained weight loss (Type 1) Blurred vision (osmotic lens changes) Fatigue, weakness, malaise Slow wound healing