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10 , e0049722 (2022)

In vivo demonstration that -synuclein oligomers are toxic

In control subjects incubation with acetylphenylhydrazine leads to a modest decrease in GSH, and a small accumulation of GSSG

Together, these data demonstrate that ablation of GSH synthesis in mice results not only in reduced expression of lipogenic enzymes but also lower levels of their corresponding lipid species