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CAS number: Refer to COA/batch-specific documentation

ILK signaling also activates c-Jun N-terminal kinase (JNK) via transcription-factor activator protein 1 (AP1) and regulates the gene expression of MMP9 41 and also IL-8 signaling 42

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This study will focus on some molecular targets, including Nuclear factor erythroid 2-related factor 2 (Nrf2), a regulatory nuclear factor that influences the activity and cellular response of the antioxidant system 17 , NF-B, and the inflammasome NLRP3 which are closely related to one another and influence the level of inflammatory and pro-fibrotic cytokines in the microenvironment as well as the apoptosis and senescence of alveolar epithelial cells especially for NF-B 18

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