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The ideal candidate is someone who has a meaningful fat-loss goal, defined as 20 lbs or more to reduce, who is also concerned about how skin quality and connective tissue integrity will hold up through that process

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Pivotal ECM components including collagen, fibronectin, and proteoglycans are upregulated in UFs compared to the adjacent myometrium (reviewed in Islam et al., 2018) and may be responsible for the increased tissue stiffness and decreased stretch

Zn transporters The interaction between zinc status and obesity may be at least partially mediated by obesity-induced modulation of zinc transporters that regulate cellular and intracellular Zn fluxes [1]