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Oral co-administration of L-arginine and L-citrulline lowered superoxide production and oxidation-sensitive genes, Elk-1 and p-CREB expression [141]

With proper treatment, the discomfort goes away

Science (2011) 334(6057):8259

320 In GBM, TGF- critically contributes to immune evasion by suppressing the cytotoxic activity of CTLs and NK cells, thereby hindering the host immune response against tumor cells