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Cytotherapy 25, 502509

So it will affect so many things, especially neural development

& Torzilli, P

This suggests that inhibition of SHMT may be one of the mechanisms through which these classical drugs exert their antitumor effects, and further validates the importance of SHMT as a drug target

Schizosaccharomyces pombe cells were grown at 32 C in Yeast Extract + Supplements (YES) medium: 0.5% w/v yeast extract, 0.2 g/l adenine, 0.2 g/l arginine, 0.2 g/l lysine, 0.2 g/l histidine, 0.2 g/l uracil, 0.2 g/l leucine