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In case of mitochondria, ROS get leakage into cytoplasm, due to which its ROS concentration increases that is responsible for the enhancement of apoptosis in the cytoplasm [44]

It heftily inhibits c-Met-driven processes like cell growth, motility, invasion, and morphology of a diversity of tumor cells [84]

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A comparison of our Sas Pcob structure with other photocobilin proteins (predicted structures obtained from the recently published Alphafold2 database 26 ), shows they can be divided into three main groups depending on the location of the AdoCbl-binding domain at either the N- or C-terminus, and whether they contain the additional output domain in the fused proteins (Supplementary Figs