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Our finding sheds new light on the contribution of export signals to T3S

T-cell activation and natural killer (NK) cell cytotoxicity are both GSH-dependent processes

Overall, indirect regulation strategies are more suitable as adjuvant treatments, and their true clinical value still requires validation through population studies

An 8- to 10-week-old male C57/BL6J mouse was anesthetized by isopentane, and the liver was washed with a perfusion buffer containing 1HBSS, 5 mM EGTA, and 55 mM Glucose

For long COVID survivors, whose immune systems may be dysregulated and prone to prolonged inflammation, understanding and potentially modulating NAD+ metabolism could offer new avenues for intervention and treatment to alleviate symptoms and improve recovery