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We are looking at different mechanisms of action for the treatment of celiac disease because nothing is approved, and we don't know what will be potentially effective for different populations, Leffler said

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This class of RNA includes a wide variety of non-coding regulatory RNAs as well as messenger RNAs mRNAs, which transfer genetic information from DNA to the translational machinery for protein synthesis

These alterations result in a significantly extended half-lifeup to 120 times longer than native IGF-1due to reduced binding affinity to insulin-like growth factor-binding proteins (IGFBPs)