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Among end-purchasers, product choices are increasingly being impacted by regulation, flavor inventory, perceived risk, and brand format

If something is safe as a food, it's not highly harmful, but we don't know what happens when you inhale it." There are concerns that nanoparticles from the vapor can be embedded in the lungs, causing inflammation and leaving the lungs vulnerable to infection

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A notable concern has been the emergence of vaping-related lung injuries, such as EVALI (e-cigarette or vaping-associated lung injury)