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The defects in mitochondrial metabolism and respiration are dependent on a block in pyruvate metabolism, as respiration was restored with pyruvate supplementation (Fu et al., 2015)

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In a previous work, our group discovered that the knockdown of genes involved in the TGFb signaling pathway protected LUHMES cells against aSyn-induced toxicity [10]

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Due to their high water content, structural similarity to natural tissues, and favorable biocompatibility, hydrogels are widely used in biomedical fields, particularly for drug delivery, facilitating controlled release and enhancing efficacy (198200)