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Key cited studies: Philp D et al

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Furthermore, heterogeneity in tumour stage (or indeed, location), patient populations and treatment dose and duration is likely to confound reported response data, particularly given the links between changes in oxidative metabolism and metastatic spread 84,85,86,87

Colocalization in images was analysed using Pearsons colocalization coefficient (Zen Imaging Software, Carl Zeiss AG) as the data was tested to be normal distributed and without outliers

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