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Clinical validation of circulating DNA analysis for the detection of point mutations and of the longitudinal metastatic colorectal patient follow up for detecting emergence of resistance to targeted therapy 76(14S), 2016

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For example, 15-deoxy (Delta)12-14PGJ2, a cyclopentenone prostaglandin derived from arachidonic acid, induces neutrophil apoptosis in rats, possibly through PPAR inactivation (123, 124)

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Additionally, non-motor symptoms include gastrointestinal (GI) disorders such as constipation, dysphagia, and delayed gastric emptying [3, 4]

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