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In parallel, Liu and colleagues demonstrated that the immunomodulatory effects of IVIg were dependent on FcRn, as they found that both experimental induction of Ab-driven autoimmune diseases and IVIg-mediated protection against the diseases were manifested in WT, but not in FcRn-deficient mice [116]

Oxidative stress, insulin signaling, and diabetes

Nature Structural Biology, 4(7), 578585

A reporting summary for this Article is available as a Supplementary Information file

Reconstitution efficiency of transhydrogenase was estimated using SDS-PAGE, visualizing the steps of the reconstitution process (soluble enzyme, low spin supernatant, high spin supernatant and pellet)