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1 H chemical shifts are expressed in ppm using the residual non-deuterated solvent as an internal standard, and the coupling constants J are specified in Hz

To a stirred solution of 3-bromo-5-(difluoromethoxy)-2-(difluoromethyl)pyridine (0.98 g, 3.6 mmol), bis(pinacolato)diboron (1.82 g, 7.2 mmol), PdCl 2 (dppf) (263 mg, 0.36 mmol), and dioxane (12 ml) was added KOAc (1.06 g, 10.8 mmol)

Bij chronische stress kunnen klachten zoals vermoeidheid, negatieve gemoedstoestand, toegenomen angst en onrust en een verminderde slaapkwaliteit ontstaan

"Salmonella typhi uses CFTR to enter intestinal epithelial cells"

doi:10.1016/j.pscychresns.2021.111302 114. Sohal, V