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Other studies have shown that enhancing SIRT1 activity using pharmacological agents can reduce different types of hearing loss, indicating that SIRT1 is a promising target for hearing protection [22, 23]

The pain can be described as sharp, burning, or aching. The pain can also feel like a jolting or pins and needles sensation

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More importantly, we found that LA supplementation could reduce the number of Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)-positive tubular cells caused by FA, indicating that the tubular cell death mediated by ferroptosis may be inhibited