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However, many clinicians and some researchers feel there is a large grey zone between 160-500 pmol/L, which in some patients could represent functional deficiency on a cellular level

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This symptom, known as jaundice, occurs when the body cannot remove bilirubin, a yellowish substance produced during the normal breakdown of red blood cells

Generally, these new strategies should be directed towards diseases with significant unmet clinical needs, including cases that have relapsed or are resistant to current treatments, as well as rare (orphan) diseases